研究チームが、魚の卵に含まれる紫外線保護物質「ガドゥソール」を生成するように細菌を改変した。この進歩は、透明で環境に優しい日焼け止めの開発を後押しする可能性がある。今回の研究は、中国の江南大学のチームが主導した。
Ping Zhang氏率いる研究チームは、ゼブラフィッシュの遺伝子を大腸菌に組み込んだ。これにより、ゼブラフィッシュ、サケ、チョウザメの卵やサンゴに微量に含まれるガドゥソールを生成するために必要な酵素が細菌に付与された。研究者らは、小さなRNA分子の使用や成長条件の調整を行うことで、以前の45.2ミリグラム/リットルという生産量から約93倍となる、4.2グラム/リットルまで生産量を引き上げることに成功した。
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Researchers at the University of Kent, working with University College London, report that madecassic acid—a compound derived from the medicinal herb Centella asiatica and widely used in skincare—can inhibit the growth of antibiotic-resistant E. coli by targeting a bacterial respiratory system not found in humans or other animals.
Researchers at Shandong University have modified the probiotic bacterium Escherichia coli Nissle 1917 to produce the anticancer drug Romidepsin directly in tumors. In mouse models of breast cancer, the engineered bacteria accumulated in tumors and released the drug. The findings were published on March 17 in PLOS Biology.
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Researchers at the University of Missouri have developed a modified strain of algae that captures microplastics from contaminated water by producing an orange-scented oil. The process also cleans wastewater and could support bioplastic production.
Researchers at University College London have discovered how the body naturally shuts down inflammation using fat-derived molecules called epoxy-oxylipins. These molecules prevent the buildup of immune cells linked to chronic diseases like arthritis and heart disease. A study involving a drug that boosts these molecules showed faster pain relief and reduced harmful immune activity.
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Researchers at EPFL have created a new membrane using lipid-coated nanopores that boosts the efficiency of blue energy production from mixing saltwater and freshwater. The innovation allows ions to pass through more smoothly, generating up to three times more power than existing technologies. This advance could make osmotic energy a more viable renewable source.