Genetics

Microscopic illustration of migrating neurons in the developing brain showing DNA damage and repair.

Developing neurons sustain and rapidly repair DNA double-strand breaks during migration, study finds

21. kesäkuuta 2026 Raportoinut AI AI:n luoma kuva Faktatarkistettu

A study in Nature reports that newborn neurons can incur double-strand DNA breaks while squeezing through tight spaces in the developing brain, and that healthy cells typically repair most of this damage within about a day.

North-western Neanderthals showed surprising genetic diversity

Genetic analysis of remains from Belgium and France indicates that some of the last Neanderthals in north-western Europe lived in diverse, connected groups. The findings suggest inbreeding was not a major factor in their extinction around 40,000 years ago.

Unapproved gene therapy for longevity set to go on sale

23. kesäkuuta 2026 Raportoinut AI

A US company plans to offer an unapproved gene therapy designed to boost levels of an anti-ageing protein called klotho. The treatment will be provided at clinics in Honduras, the Bahamas and Panama. It aims to bypass US regulatory requirements.

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Ancient Denisovan DNA still shapes human immunity today

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Gene mutation identified as cause of rare spastic ataxia

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Ancient DNA shared with Neanderthals may explain human language

Study finds blood-cancer-linked mutations in brain immune cells tied to Alzheimer’s pathology

Researchers at Boston Children’s Hospital report that mutations commonly associated with clonal blood-cell expansion and some blood cancers were enriched in microglia-like immune cells in Alzheimer’s brains and were also detectable in matched blood samples. The Cell study proposes that age- or injury-related weakening of the blood-brain barrier could allow mutated blood immune cells to enter the brain, potentially amplifying inflammation and contributing to neurodegeneration.

Large study uncovers endometriosis genetic links across ancestries

08. kesäkuuta 2026 Raportoinut AI

A major analysis of data from more than a million women has identified hundreds of genes tied to endometriosis. The research also connects the condition to inflammation, cholesterol regulation and gut bacteria changes.

Large genetic study uncovers new Alzheimer’s drug targets

A major analysis of genetic data has linked 127 gene locations to Alzheimer’s disease, including 48 previously unidentified ones. Researchers also flagged several genes as promising drug targets and highlighted changes in immune and nerve cells.

Study finds epigenetic traits break Mendel's genetic laws

01. kesäkuuta 2026 Raportoinut AI

A federally funded mouse study has revealed that some inherited traits follow non-Mendelian patterns through epigenetic changes. The research identified hundreds of unexpected DNA methylation events across generations. It also documented the first known natural paramutation in a mammal.

21. kesäkuuta 2026 03.33