Genetics
Developing neurons sustain and rapidly repair DNA double-strand breaks during migration, study finds
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A study in Nature reports that newborn neurons can incur double-strand DNA breaks while squeezing through tight spaces in the developing brain, and that healthy cells typically repair most of this damage within about a day.
Researchers have discovered ancient human DNA on cave walls and rock art in Spain and Portugal, marking the first such finding on prehistoric paintings. The breakthrough could eventually help identify individual artists from thousands of years ago.
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Researchers have identified the gene NANOG as the key switch that initiates the developmental program resulting in cells forming a human body. The finding came from precise DNA edits to fertilized human eggs using CRISPR base editing.
Researchers have discovered that mutations in the CD99L2 gene cause X-linked spastic ataxia, a rare movement disorder. The finding came from analysis of 2,811 patients with conditions affecting coordination and muscle control. The study was published in Nature Communications.
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A newly published study suggests that a tiny fraction of human DNA plays an outsized role in language ability. Researchers at the University of Iowa found these genetic regions were present before modern humans and Neanderthals diverged. The findings push back the timeline for the biological basis of language.
A long-term DNA study of beluga whales in Alaska has revealed that both males and females regularly change mating partners over their lifetimes.
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Cold Spring Harbor Laboratory researchers report that a feedback circuit involving the proteins MYRF-1 and LIN-42 times organism-wide bursts of gene activity that help drive the roundworm C. elegans through its larval stages.
North-western Neanderthals showed surprising genetic diversity
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