CRISPR Tool Targets Neuron Gene Repair

15 settembre 2025 Riportato dall'IA

Stanford researchers have created a CRISPR-based technology to target RNA in neurons, enabling repair processes for genetic diseases. The method addresses key challenges in Cas9 delivery and DNA repair. It reveals unique genome editing rules in neurons, paving the way for targeted therapies.

Study shows older fathers transmit more disease mutations through selfish sperm

A new study reveals that older men pass on significantly more disease-causing genetic mutations to their children due to the rapid proliferation of mutant sperm stem cells. Researchers found that the proportion of mutated sperm rises sharply with age, from 1 in 50 for men in their early thirties to nearly 1 in 20 by age 70. This phenomenon, driven by 'selfish' mutations, heightens risks for severe disorders in offspring.

Illumina AI Tool for Rare Diseases

11 settembre 2025 Riportato dall'IA

Illumina introduced an AI tool aiding in the diagnosis of rare diseases. This innovation enhances genetic analysis for complex conditions. It was highlighted in biotech news updates.

Evolution of human intelligence linked to mental illness vulnerability

11 ottobre 2025 Riportato dall'IA

Researchers have traced genetic variants in the human genome to reveal that advances in cognitive abilities around 500,000 years ago were soon followed by mutations increasing susceptibility to psychiatric disorders. This suggests a trade-off in brain evolution. The study, published in Cerebral Cortex, analyzed 33,000 genetic variants to build an evolutionary timeline of brain-related traits.

Gene mutation raises disease risk by 50 percent

A new study has identified a specific gene mutation that increases the risk of type 2 diabetes by 50 percent. Led by researchers at the University of California, Berkeley, the findings come from a five-year analysis of 1,000 participants. The discovery highlights potential pathways for early detection and treatment.