Study overturns idea that light drinking protects brain health

October 05, 2025 Ti AI ṣe iroyin

A large-scale study combining observational and genetic data has found that any alcohol consumption increases dementia risk, with no safe level identified. Published in BMJ Evidence Based Medicine, the research challenges previous beliefs about moderate drinking's benefits. Dementia risk rises linearly with alcohol intake, according to the analysis.

CRISPR Tool Targets Neuron Gene Repair

September 15, 2025 Ti AI ṣe iroyin

Stanford researchers have created a CRISPR-based technology to target RNA in neurons, enabling repair processes for genetic diseases. The method addresses key challenges in Cas9 delivery and DNA repair. It reveals unique genome editing rules in neurons, paving the way for targeted therapies.

Study shows older fathers transmit more disease mutations through selfish sperm

October 09, 2025 Ti AI ṣe iroyin

A new study reveals that older men pass on significantly more disease-causing genetic mutations to their children due to the rapid proliferation of mutant sperm stem cells. Researchers found that the proportion of mutated sperm rises sharply with age, from 1 in 50 for men in their early thirties to nearly 1 in 20 by age 70. This phenomenon, driven by 'selfish' mutations, heightens risks for severe disorders in offspring.

Illumina AI Tool for Rare Diseases

Illumina introduced an AI tool aiding in the diagnosis of rare diseases. This innovation enhances genetic analysis for complex conditions. It was highlighted in biotech news updates.

DNA scar catalog opens paths to overcome cancer drug resistances

Researchers at Spain's National Cancer Research Centre (CNIO) have developed a comprehensive catalog of mutational 'scars' in DNA caused by cancer. This breakthrough, published in Nature, could help bypass resistances to treatments like PARP inhibitors. The study analyzes thousands of tumor samples to identify key genetic patterns.