Omprogrammering av stamceller bygger större muskler hos åldrande möss

Forskare har visat att föryngring av muskelstamceller från gamla möss leder till större muskeltillväxt och förbättrad återhämtning efter skador. Metoden skulle en dag kunna hjälpa äldre människor att återfå styrka och rörlighet. Experimenten visade tydliga fördelar för benfunktion och vävnadsläkning.

Forskare vid Duke University extraherade muskelstamceller från åldrande möss, kompletterade dem med specifika lipider i laboratoriet och injicerade sedan de behandlade cellerna i skadade muskler hos andra gamla möss. De behandlade cellerna producerade nya muskelfibrer som var 45 procent större än de från obehandlade celler, och mössen uppvisade bättre resultat i löpbandstester och rörlighetstester inom loppet av några dagar.

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