Caribou Biosciences sampaikan pembaruan car-t di konferensi kesehatan

Caribou Biosciences mendiskusikan perkembangan terapi CAR-T siap pakai dalam sebuah presentasi di Bank of America Global Healthcare Conference pada 13 Mei. Direktur Utama Rachel Haurwitz menyoroti data Fase I untuk dua program yang menargetkan limfoma dan multiple myeloma.

Perusahaan sedang mengembangkan Vispa-cel, yang menargetkan CD19 untuk limfoma, dan CB-011, yang menargetkan BCMA untuk multiple myeloma. Kedua program tersebut menerima pembaruan klinis yang signifikan pada akhir tahun lalu, dan hasil awal mendukung potensi terbaik di kelasnya, kata Haurwitz dalam sesi yang dipandu oleh analis Alec Stranahan.

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Illustration of a German woman achieving complete remission from three autoimmune diseases via groundbreaking CAR-T therapy, symbolizing hope and medical triumph.
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CAR-T therapy achieves complete remission of three autoimmune diseases in German woman

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A 47-year-old woman bedridden with autoimmune hemolytic anemia, immune thrombocytopenia, and antiphospholipid syndrome has achieved complete remission after CAR-T cell therapy at University Hospital Erlangen in Germany. Treated by Fabian Müller after nine failed therapies, she recovered rapidly and remains healthy over a year later without medication—the first simultaneous treatment of multiple autoimmune diseases with this method.

Researchers tested a redesigned CD40 agonist antibody, 2141-V11, by injecting it directly into tumors of 12 patients with metastatic cancers. Six patients saw tumor shrinkage, with two achieving complete remission, including effects on untreated tumors elsewhere in the body. The trial reported only mild side effects, unlike prior CD40 therapies.

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AbCellera Biologics Inc. has released a slide deck related to its fourth-quarter 2025 results. The presentation accompanies the company's earnings call. It was published on February 24, 2026.

Researchers at Fred Hutch Cancer Center have created human-like monoclonal antibodies that prevent Epstein-Barr virus (EBV) from infecting immune cells. Using mice engineered with human antibody genes, the team identified antibodies targeting viral proteins gp350 and gp42, with one fully blocking infection in lab models. The findings, published in Cell Reports Medicine, could lead to therapies for transplant patients at risk of EBV-related complications.

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Scientists from ITQB NOVA and the Portuguese Institute of Oncology have started the BRIDGE project to uncover how aggressive breast cancer evades the immune system. The initiative seeks biomarkers for better prediction of disease progression and personalized treatments. Funded with up to €75,000, the two-year effort uses patient samples to validate lab findings.

A Japanese health panel has approved national health insurance coverage for Sumitomo Pharma's Amchepry, an iPS cell-derived treatment for Parkinson’s disease. The move makes it the world's first commercialized medical product from iPS cells.

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Nuvation Bio Inc. conducted its first quarter 2026 earnings call on May 4, 2026. The company reviewed financial results for the period ending March 31, 2026, and provided a business update. Executives including CEO David Hung participated in the discussion.

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