Para peneliti luncurkan proyek BRIDGE mengenai kanker payudara agresif

Para ilmuwan dari ITQB NOVA dan Institut Onkologi Portugal telah memulai proyek BRIDGE untuk mengungkap bagaimana kanker payudara agresif menghindari sistem kekebalan tubuh. Inisiatif ini mencari biomarker untuk prediksi perkembangan penyakit yang lebih baik serta perawatan yang dipersonalisasi. Didanai hingga €75.000, upaya dua tahun ini menggunakan sampel pasien untuk memvalidasi temuan laboratorium.

Proyek BRIDGE, singkatan dari Biomarker Research Integrating Data of Glyco-Immune Signatures and Clinical Evidence in Breast Cancer, menargetkan lingkungan mikro tumor di mana sel kanker berinteraksi dengan sel kekebalan tubuh. Para peneliti bertujuan untuk mengidentifikasi molekul kecil pada permukaan sel yang memungkinkan tumor menekan deteksi kekebalan, yang menyebabkan pertumbuhan yang tidak terkendali. Hal ini didasarkan pada penemuan sebelumnya mengenai komunikasi tumor-imun, yang kini diuji dengan sampel pasien nyata dari IPOFG.

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