Mengeraskan sel kanker meningkatkan terapi sel T-CAR pada tikus

Jumat, 15 Mei 2026

Dilaporkan oleh AI

Para peneliti menemukan bahwa membuat sel kanker menjadi lebih keras dapat meningkatkan efektivitas terapi sel T-CAR terhadap tumor agresif. Dalam eksperimen pada tikus, pendekatan ini menyebabkan tumor menghilang sepenuhnya dalam beberapa kasus. Temuan tersebut dipresentasikan baru-baru ini dalam sebuah konferensi di London.

Sel kanker sering kali lebih lunak daripada sel sehat karena kadar kolesterol yang lebih tinggi di dalam membrannya. Kelembutan ini mungkin membantu sel kanker menghindari serangan kekebalan tubuh. Para ilmuwan di Swiss Federal Technology Institute of Lausanne menguji apakah mengeraskan sel-sel ini dapat meningkatkan hasil imunoterapi.

McGill researchers use reversible drug approach to boost natural killer cells against hard-to-treat cancers

Senin, 25 Mei 2026 Dilaporkan oleh AI Gambar dihasilkan oleh AI Fakta terverifikasi

Researchers at McGill University report a drug-based method to temporarily enhance natural killer (NK) cells—an immune cell type—by inhibiting two proteins, improving the cells’ ability to attack several aggressive cancers in preclinical experiments.

3D-printed structures could speed up car t-cell therapy

Researchers have developed 3D-printed gels that mimic lymph nodes to improve the production of CAR T-cells for cancer treatment. The approach increased success rates and sped up cell growth compared with standard methods. It may help lower costs and expand access to the therapy worldwide.

Protein found to limit CAR T-cell therapy effectiveness

Selasa, 02 Juni 2026 Dilaporkan oleh AI

A protein called NFIL3 has been identified as a key factor in reducing the long-term performance of CAR T cells used in cancer treatment. Researchers showed that disabling this protein allows the engineered cells to remain active longer and fight tumors more effectively in laboratory models.

Health

29 Juni 2026 21.11

Mengeraskan sel kanker meningkatkan terapi sel T-CAR pada tikus

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