Endurecer las células cancerosas potencia la terapia con células CAR-T en ratones

15 de mayo de 2026

Reportado por IA

Investigadores han descubierto que endurecer las células cancerosas puede mejorar la eficacia de la terapia con células CAR-T contra tumores agresivos. En experimentos con ratones, el enfoque condujo a la desaparición completa de los tumores en algunos casos. Los hallazgos fueron presentados recientemente en una conferencia en Londres.

Las células cancerosas son a menudo más blandas que las sanas debido a niveles más altos de colesterol en sus membranas. Esta blandura puede ayudarlas a evadir los ataques del sistema inmunológico. Científicos del Instituto Federal Suizo de Tecnología de Lausana probaron si endurecer estas células podría mejorar los resultados de la inmunoterapia.

McGill researchers use reversible drug approach to boost natural killer cells against hard-to-treat cancers

25 de mayo de 2026 Reportado por IA Imagen generada por IA Verificado por hechos

Researchers at McGill University report a drug-based method to temporarily enhance natural killer (NK) cells—an immune cell type—by inhibiting two proteins, improving the cells’ ability to attack several aggressive cancers in preclinical experiments.

3D-printed structures could speed up car t-cell therapy

Researchers have developed 3D-printed gels that mimic lymph nodes to improve the production of CAR T-cells for cancer treatment. The approach increased success rates and sped up cell growth compared with standard methods. It may help lower costs and expand access to the therapy worldwide.

Protein found to limit CAR T-cell therapy effectiveness

2 de junio de 2026 Reportado por IA

A protein called NFIL3 has been identified as a key factor in reducing the long-term performance of CAR T cells used in cancer treatment. Researchers showed that disabling this protein allows the engineered cells to remain active longer and fight tumors more effectively in laboratory models.

Health

29 de junio de 2026 21:11

Endurecer las células cancerosas potencia la terapia con células CAR-T en ratones

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