Científicos descubren que la proteína MYC ayuda a los cánceres a resistir la quimioterapia

17 de mayo de 2026

Reportado por IA

Un nuevo estudio revela que la proteína MYC hace más que impulsar el crecimiento tumoral. También repara el daño en el ADN de las células cancerosas, lo que permite que algunos tumores sobrevivan a la quimioterapia y a la radiación.

Investigadores de la Oregon Health & Science University descubrieron que la MYC se desplaza a los sitios donde el ADN está roto y recluta proteínas de reparación. Este papel no tradicional ayuda a las células tumorales a recuperarse de los tratamientos destinados a destruirlas, según la autora principal Rosalie Sears.

Study finds excessive EXO1 DNA-repair activity can destabilize genomes and may mark tumors sensitive to some therapies

20 de junio de 2026 Reportado por IA Imagen generada por IA Verificado por hechos

Researchers at Penn State College of Medicine report that unusually high activity of the DNA-repair gene EXO1 can damage newly replicated DNA and create BRCA-like weaknesses in some tumors, potentially helping identify patients who could respond to certain treatments used for BRCA-mutant cancers.

McGill researchers use reversible drug approach to boost natural killer cells against hard-to-treat cancers

Researchers at McGill University report a drug-based method to temporarily enhance natural killer (NK) cells—an immune cell type—by inhibiting two proteins, improving the cells’ ability to attack several aggressive cancers in preclinical experiments.

Protein found to limit CAR T-cell therapy effectiveness

2 de junio de 2026 Reportado por IA

A protein called NFIL3 has been identified as a key factor in reducing the long-term performance of CAR T cells used in cancer treatment. Researchers showed that disabling this protein allows the engineered cells to remain active longer and fight tumors more effectively in laboratory models.

Health

Científicos descubren que la proteína MYC ayuda a los cánceres a resistir la quimioterapia

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