Cientistas descobrem que proteína MYC ajuda cânceres a resistir à quimioterapia

17 de maio de 2026

Reportado por IA

Um novo estudo revela que a proteína MYC faz mais do que impulsionar o crescimento de tumores. Ela também repara danos no DNA em células cancerígenas, permitindo que alguns tumores sobrevivam à quimioterapia e à radiação.

Pesquisadores da Oregon Health & Science University descobriram que a MYC se desloca para locais de DNA danificado e recruta proteínas de reparo. Esse papel não tradicional ajuda as células tumorais a se recuperarem de tratamentos destinados a destruí-las, de acordo com a autora sênior Rosalie Sears.

Study finds excessive EXO1 DNA-repair activity can destabilize genomes and may mark tumors sensitive to some therapies

20 de junho de 2026 Reportado por IA Imagem gerada por IA Verificado

Researchers at Penn State College of Medicine report that unusually high activity of the DNA-repair gene EXO1 can damage newly replicated DNA and create BRCA-like weaknesses in some tumors, potentially helping identify patients who could respond to certain treatments used for BRCA-mutant cancers.

McGill researchers use reversible drug approach to boost natural killer cells against hard-to-treat cancers

Researchers at McGill University report a drug-based method to temporarily enhance natural killer (NK) cells—an immune cell type—by inhibiting two proteins, improving the cells’ ability to attack several aggressive cancers in preclinical experiments.

Protein found to limit CAR T-cell therapy effectiveness

02 de junho de 2026 Reportado por IA

A protein called NFIL3 has been identified as a key factor in reducing the long-term performance of CAR T cells used in cancer treatment. Researchers showed that disabling this protein allows the engineered cells to remain active longer and fight tumors more effectively in laboratory models.

Health

Cientistas descobrem que proteína MYC ajuda cânceres a resistir à quimioterapia

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