Ilmuwan menemukan protein MYC membantu kanker melawan kemoterapi

Minggu, 17 Mei 2026

Dilaporkan oleh AI

Sebuah studi baru mengungkapkan bahwa protein MYC memiliki peran lebih dari sekadar mendorong pertumbuhan tumor. Protein ini juga memperbaiki kerusakan DNA pada sel kanker, sehingga memungkinkan beberapa tumor bertahan dari kemoterapi dan radiasi.

Para peneliti di Oregon Health & Science University menemukan bahwa MYC berpindah ke lokasi DNA yang rusak dan merekrut protein perbaikan. Peran nontradisional ini membantu sel tumor pulih dari pengobatan yang ditujukan untuk menghancurkannya, menurut penulis senior Rosalie Sears.

Study finds excessive EXO1 DNA-repair activity can destabilize genomes and may mark tumors sensitive to some therapies

Sabtu, 20 Juni 2026 Dilaporkan oleh AI Gambar dihasilkan oleh AI Fakta terverifikasi

Researchers at Penn State College of Medicine report that unusually high activity of the DNA-repair gene EXO1 can damage newly replicated DNA and create BRCA-like weaknesses in some tumors, potentially helping identify patients who could respond to certain treatments used for BRCA-mutant cancers.

McGill researchers use reversible drug approach to boost natural killer cells against hard-to-treat cancers

Researchers at McGill University report a drug-based method to temporarily enhance natural killer (NK) cells—an immune cell type—by inhibiting two proteins, improving the cells’ ability to attack several aggressive cancers in preclinical experiments.

Protein found to limit CAR T-cell therapy effectiveness

Selasa, 02 Juni 2026 Dilaporkan oleh AI

A protein called NFIL3 has been identified as a key factor in reducing the long-term performance of CAR T cells used in cancer treatment. Researchers showed that disabling this protein allows the engineered cells to remain active longer and fight tumors more effectively in laboratory models.

Health

Ilmuwan menemukan protein MYC membantu kanker melawan kemoterapi

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