Ilmuwan temukan sirkuit usus-otak yang memicu keinginan mengonsumsi protein

Kamis, 28 Mei 2026

Dilaporkan oleh AI

Para peneliti telah mengidentifikasi jaringan sinyal antara usus dan otak yang sebelumnya tidak diketahui, yang mendeteksi kekurangan protein dan mengalihkan preferensi makan terhadap asam amino esensial.

Tim yang dipimpin oleh Direktur SUH Seong-Bae di Institute for Basic Science, bersama rekan-rekan dari Seoul National University dan Ewha Womans University, memetakan mekanisme tersebut pada lalat buah dan mengonfirmasi perilaku serupa pada tikus. Penelitian ini diterbitkan dalam jurnal Science pada tanggal 21 Mei.

Childhood junk food may leave lasting changes in brain circuits that guide eating, mouse study suggests

Kamis, 21 Mei 2026 Dilaporkan oleh AI Gambar dihasilkan oleh AI Fakta terverifikasi

Researchers at APC Microbiome Ireland at University College Cork report that early-life exposure to a high-fat, high-sugar diet altered feeding behavior and appetite-related brain pathways in mice into adulthood, even after the animals returned to a standard diet and normal body weight. The team also found that a specific Bifidobacterium strain and a prebiotic fiber mix helped mitigate some of these long-term effects.

Intestinal cells signal brain to curb hunger during parasitic infections

A team led by David Julius, the 2021 Nobel Prize winner in Medicine, has described the molecular mechanism by which intestinal tuft cells signal the brain to suppress appetite during parasitic infections. Published today in Nature, the study identifies communication via acetylcholine and serotonin that activates the vagus nerve. The finding could aid treatments for conditions like irritable bowel syndrome.

Researchers map hindbrain circuit through which hormone FGF21 drives weight loss in obese mice

Jumat, 17 April 2026 Dilaporkan oleh AI Fakta terverifikasi

University of Oklahoma scientists report that the hormone FGF21 reduces body weight in obese mice by acting on a hindbrain pathway—centered on the nucleus of the solitary tract and area postrema—that relays signals to the parabrachial nucleus. The team says the mechanism overlaps anatomically with brain regions implicated in GLP-1 drugs, but appears to promote weight loss mainly by increasing metabolic rate rather than primarily suppressing food intake.

Kesehatan

Intermittent energy restriction tied to shifts in brain activity and gut microbiome, small study suggests

Kesehatan

Brain protein decline linked to aging in mice study

Kesehatan

Study links early childhood stress to lifelong digestive problems

Japanese study links GLP-1 response to ‘external eating’ habits in people with type 2 diabetes

A year-long observational study in Japan suggests that people with type 2 diabetes who tend to overeat in response to tempting food cues such as sight and smell may see greater weight loss—and possibly better blood-sugar improvement—after starting GLP-1 receptor agonists, while those with primarily emotional eating patterns show less consistent links to long-term outcomes.

Scientists identify brain circuit for chronic pain transition

Senin, 27 April 2026 Dilaporkan oleh AI

Researchers at the University of Colorado Boulder have pinpointed a brain region called the caudal granular insular cortex, or CGIC, that acts as a switch turning acute pain into chronic pain. In animal studies, disabling this circuit prevented chronic pain from developing or reversed it once established. The findings, published in the Journal of Neuroscience, open paths to new treatments beyond opioids.

08 Juni 2026 15.34

Ilmuwan temukan sirkuit usus-otak yang memicu keinginan mengonsumsi protein

Artikel Terkait

Childhood junk food may leave lasting changes in brain circuits that guide eating, mouse study suggests

Intestinal cells signal brain to curb hunger during parasitic infections

Researchers map hindbrain circuit through which hormone FGF21 drives weight loss in obese mice

Intermittent energy restriction tied to shifts in brain activity and gut microbiome, small study suggests

Brain protein decline linked to aging in mice study

Study links early childhood stress to lifelong digestive problems

Japanese study links GLP-1 response to ‘external eating’ habits in people with type 2 diabetes

Scientists identify brain circuit for chronic pain transition

Mouse study links acetylcholine bursts in the striatum to switching away from failed habits

Scientists reverse anxiety behaviors in mice by fixing brain circuit

AI tool maps obesity-linked changes in facial sensory nerves across whole mouse bodies

Scientists identify molecular switch that limits scratching

Scientists map organized smell receptors in mouse noses

Study links hypothalamic astrocytes to a post-meal satiety signal triggered by tanycyte-derived lactate

Study finds some common gut bacteria can inject proteins into human cells

Situs web ini menggunakan cookie