Cientistas descobrem circuito intestino-cérebro que desencadeia desejo por proteínas

28 de maio de 2026

Reportado por IA

Pesquisadores identificaram uma rede de sinalização anteriormente desconhecida entre o intestino e o cérebro que detecta a escassez de proteínas e direciona as preferências alimentares para aminoácidos essenciais.

Uma equipe liderada pelo diretor SUH Seong-Bae do Institute for Basic Science, juntamente com colegas da Seoul National University e da Ewha Womans University, mapeou o mecanismo em moscas-das-frutas e confirmou um comportamento semelhante em camundongos. O trabalho foi publicado na revista Science em 21 de maio.

Childhood junk food may leave lasting changes in brain circuits that guide eating, mouse study suggests

21 de maio de 2026 Reportado por IA Imagem gerada por IA Verificado

Researchers at APC Microbiome Ireland at University College Cork report that early-life exposure to a high-fat, high-sugar diet altered feeding behavior and appetite-related brain pathways in mice into adulthood, even after the animals returned to a standard diet and normal body weight. The team also found that a specific Bifidobacterium strain and a prebiotic fiber mix helped mitigate some of these long-term effects.

Intestinal cells signal brain to curb hunger during parasitic infections

A team led by David Julius, the 2021 Nobel Prize winner in Medicine, has described the molecular mechanism by which intestinal tuft cells signal the brain to suppress appetite during parasitic infections. Published today in Nature, the study identifies communication via acetylcholine and serotonin that activates the vagus nerve. The finding could aid treatments for conditions like irritable bowel syndrome.

Researchers map hindbrain circuit through which hormone FGF21 drives weight loss in obese mice

17 de abril de 2026 Reportado por IA Verificado

University of Oklahoma scientists report that the hormone FGF21 reduces body weight in obese mice by acting on a hindbrain pathway—centered on the nucleus of the solitary tract and area postrema—that relays signals to the parabrachial nucleus. The team says the mechanism overlaps anatomically with brain regions implicated in GLP-1 drugs, but appears to promote weight loss mainly by increasing metabolic rate rather than primarily suppressing food intake.

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Intermittent energy restriction tied to shifts in brain activity and gut microbiome, small study suggests

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Brain protein decline linked to aging in mice study

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Study links early childhood stress to lifelong digestive problems

Japanese study links GLP-1 response to ‘external eating’ habits in people with type 2 diabetes

A year-long observational study in Japan suggests that people with type 2 diabetes who tend to overeat in response to tempting food cues such as sight and smell may see greater weight loss—and possibly better blood-sugar improvement—after starting GLP-1 receptor agonists, while those with primarily emotional eating patterns show less consistent links to long-term outcomes.

Scientists identify brain circuit for chronic pain transition

27 de abril de 2026 Reportado por IA

Researchers at the University of Colorado Boulder have pinpointed a brain region called the caudal granular insular cortex, or CGIC, that acts as a switch turning acute pain into chronic pain. In animal studies, disabling this circuit prevented chronic pain from developing or reversed it once established. The findings, published in the Journal of Neuroscience, open paths to new treatments beyond opioids.

segunda-feira, 08 de junho de 2026, 15:34h

Cientistas descobrem circuito intestino-cérebro que desencadeia desejo por proteínas

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