ケンブリッジ大学の研究チームは、人の脳と脊髄を模した小型のラボグロウンモデル（オルガノイド）を開発し、特定の条件下で損傷した神経線維の再生能力が回復することを示した。
研究チームは、幹細胞由来のオルガノイドを物理的に分離した状態で維持し、機能的な神経回路を構築した。脳組織から伸びた軸索が隙間を越えて脊髄組織と接続し、筋肉の収縮を引き起こした。この実験系を用いることで、1年以上の発達過程にわたる再生の研究が可能となった。
AIによるレポート AIによって生成された画像 事実確認済み
Duke University researchers report that boosting the transfer of healthy mitochondria from support cells to sensory neurons reduced pain-like behaviors in mouse models of diabetic and chemotherapy-related peripheral neuropathy, an approach they say could address a root driver of nerve pain rather than simply blocking pain signals.
Researchers in Japan have created new vitamin K compounds that are three times more effective than natural forms at turning stem cells into neurons. The work, published in 2025, targets diseases that destroy brain cells such as Alzheimer’s and Parkinson’s.
AIによるレポート
Researchers have shown that rejuvenating muscle stem cells from old mice leads to larger muscle growth and improved recovery after injury. The approach could one day help older people regain strength and mobility. Experiments demonstrated clear benefits in leg function and tissue repair.
A widely studied anti-aging treatment triggered significant brain damage in mice, according to new research from the University of Connecticut. The drug combination dasatinib plus quercetin caused myelin loss and changes resembling those seen in multiple sclerosis. The findings raise questions about its use in longevity studies and off-label therapies.