CAR-T細胞療法、HIV抑制に初期の可能性

小規模な研究により、CAR-T細胞療法がHIVの長期的な管理に向けた新しい手法となる可能性が示された。特定のガンの治療にすでに用いられているこの手法は、患者自身の免疫細胞を遺伝子改変するものだ。

研究者らは、2人の被験者において肯定的な初期兆候が見られたことを受け、HIV治療への転用を試みている。この改変細胞は、継続的な介入なしにウイルスを抑制する一助となる可能性がある。

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Illustration of a German woman achieving complete remission from three autoimmune diseases via groundbreaking CAR-T therapy, symbolizing hope and medical triumph.
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CAR-T therapy achieves complete remission of three autoimmune diseases in German woman

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A 47-year-old woman bedridden with autoimmune hemolytic anemia, immune thrombocytopenia, and antiphospholipid syndrome has achieved complete remission after CAR-T cell therapy at University Hospital Erlangen in Germany. Treated by Fabian Müller after nine failed therapies, she recovered rapidly and remains healthy over a year later without medication—the first simultaneous treatment of multiple autoimmune diseases with this method.

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