Estudo associa células sanguíneas humanas a ancestrais de 700 milhões de anos

Pesquisadores da Universidade de Kyoto rastrearam a origem das células sanguíneas humanas até organismos unicelulares que viveram há cerca de 700 milhões de anos. A análise mostra que as células imunológicas modernas refletem uma antiga trajetória evolutiva que remonta ao surgimento de animais multicelulares.

A equipe desenvolveu um novo método para comparar a expressão gênica entre tipos celulares e espécies. Essa abordagem permitiu construir árvores evolutivas para linhagens de células sanguíneas e identificar semelhanças com organismos unicelulares. Os macrófagos apresentaram as ligações mais próximas a esses ancestrais primitivos, sugerindo que representam a forma mais antiga de células sanguíneas.

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