Des chercheurs de l'USC identifient des composés ciblant l'inflammation cérébrale liée à la maladie d'Alzheimer

26 mai 2026

Rapporté par l'IA

Des scientifiques de l'Université de Californie du Sud ont découvert des composés expérimentaux susceptibles de réduire l'inflammation cérébrale nocive associée à la maladie d'Alzheimer. Les travaux se concentrent sur l'enzyme cPLA2 et sur les personnes porteuses du gène à haut risque APOE4.

Des chercheurs de l'Université de Californie du Sud ont identifié des composés qui inhibent sélectivement la cPLA2, une enzyme liée à l'inflammation dans le cerveau. Ces résultats ont été publiés en 2026 dans la revue npj Drug Discovery. L'équipe a établi un lien entre une activité accrue de la cPLA2 et un risque plus élevé de maladie d'Alzheimer chez les porteurs du gène APOE4, bien que cette enzyme joue également un rôle dans le fonctionnement normal du cerveau.

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mercredi 20 mai 2026 09h20

Des chercheurs de l'USC identifient des composés ciblant l'inflammation cérébrale liée à la maladie d'Alzheimer

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