Studie kopplar lägre normala B12-nivåer till hjärnförändringar

Svenska

En studie från University of California San Francisco har kopplat lägre, men fortfarande normala, nivåer av aktivt vitamin B12 till långsammare tankeprocesser och skador på vit substans hos friska äldre vuxna. Forskningen, som publicerades i Annals of Neurology 2025, tyder på att nuvarande riktlinjer kan missa tidiga neurologiska risker. Forskarna undersökte 231 deltagare med en medelålder på 71 år.

Studien fokuserade på äldre vuxna utan demens eller lindrig kognitiv svikt. Deltagarna hade en genomsnittlig B12-nivå i blodet på 414,8 pmol/L, vilket är långt över det amerikanska minimivärdet på 148 pmol/L. De med lägre aktivt B12 uppvisade långsammare bearbetningshastighet och fördröjda visuella responser efter justeringar för ålder, kön, utbildning och kardiovaskulära risker.

Relaterade artiklar

Realistic illustration of a fatigued young adult overlaid with brain MRI and blood cell visuals highlighting altered ATP energy patterns linked to depression.
Bild genererad av AI

Study links major depression in young adults to altered cellular energy patterns in brain and blood

Rapporterad av AI Bild genererad av AI Faktagranskad

Researchers studying young adults with major depressive disorder have reported an unusual energy “signature” in both the brain and immune blood cells: higher ATP-related measures at rest, paired with a reduced ability to increase energy production when demand rises. The findings, published in Translational Psychiatry, may help explain common symptoms such as fatigue and low motivation, though the work is early and based on a small sample.

Higher midlife vitamin D levels linked to lower brain tau protein

A new study has found that adults with higher vitamin D levels in their 30s and 40s tend to have lower levels of tau protein in their brains about 16 years later. Tau is a key biomarker associated with dementia. The research, published this week, highlights a potential modifiable risk factor for brain health.

Study links brain blood flow changes to Alzheimer's risk

Rapporterad av AI

New research from the University of Southern California suggests that subtle declines in brain blood flow and oxygen delivery may be early indicators of Alzheimer's disease. The study, published in Alzheimer's and Dementia, used noninvasive scans to connect vascular health with amyloid plaques and hippocampal shrinkage. These findings highlight the role of brain circulation in the disease process beyond traditional markers like amyloid and tau.

Hälsa

Stroke prompts rejuvenation-like changes in undamaged brain areas

Hälsa

Regular egg eating linked to lower Alzheimer’s risk

Hälsa

Lonely older adults have weaker memory but similar decline rates

Blood test forecasts Alzheimer's symptoms years ahead

Scientists at Washington University School of Medicine in St. Louis have developed a blood test that estimates when Alzheimer's symptoms may begin, using levels of the protein p-tau217. The model predicts onset within about three to four years, potentially aiding clinical trials and early interventions. This advance relies on data from 603 older adults in ongoing studies.

UCSF study links iron-associated protein FTL1 to age-related memory decline in mice

Rapporterad av AI Faktagranskad

Researchers at the University of California, San Francisco report that higher levels of the iron-associated protein FTL1 in the hippocampus of older mice are tied to weaker neural connections and worse performance on cognitive tests. In the experiments, reducing FTL1 in older mice was associated with increased neuronal connectivity and improved memory performance, findings published in Nature Aging.

21 maj 2026 17:55

Women’s verbal memory may delay alzheimer’s diagnosis by years

20 maj 2026 20:53

Study finds alzheimer's risk factors hit women harder

24 april 2026 18:54

Personalized treatment plans improve early dementia symptoms

15 april 2026 04:46

Lifelong cognitive enrichment tied to lower Alzheimer’s risk and later symptom onset, study finds

19 mars 2026 08:40

Higher meat intake slows Alzheimer's decline for APOE4 carriers, Karolinska study shows

Denna webbplats använder cookies

Vi använder cookies för analys för att förbättra vår webbplats. Läs vår integritetspolicy för mer information.
Avböj