دراسة تربط بين مستويات فيتامين ب12 الطبيعية المنخفضة وتغيرات في الدماغ

22 مايو، 2026

من إعداد الذكاء الاصطناعي

ربطت دراسة أجرتها جامعة كاليفورنيا في سان فرانسيسكو بين المستويات المنخفضة -التي لا تزال ضمن النطاق الطبيعي- من فيتامين ب12 النشط وبين بطء التفكير وتلف المادة البيضاء لدى كبار السن الأصحاء. وتشير الأبحاث المنشورة في دورية Annals of Neurology عام 2025 إلى أن الإرشادات الحالية قد تغفل عن مخاطر عصبية مبكرة. وقد فحص الباحثون 231 مشاركاً بمتوسط عمر بلغ 71 عاماً.

ركزت الدراسة على كبار السن ممن لا يعانون من الخرف أو الضعف الإدراكي الخفيف. وكان متوسط مستوى فيتامين ب12 في الدم لدى المشاركين 414.8 بيكومول/لتر، وهو أعلى بكثير من الحد الأدنى الأمريكي البالغ 148 بيكومول/لتر. وأظهر أولئك الذين لديهم مستويات أقل من فيتامين ب12 النشط بطئاً في سرعة المعالجة وتأخراً في الاستجابات البصرية بعد إجراء تعديلات بناءً على العمر والجنس والتعليم والمخاطر القلبية الوعائية.

Study links major depression in young adults to altered cellular energy patterns in brain and blood

12 مارس، 2026 من إعداد الذكاء الاصطناعي صورة مولدة بواسطة الذكاء الاصطناعي تم التحقق من الحقائق

Researchers studying young adults with major depressive disorder have reported an unusual energy “signature” in both the brain and immune blood cells: higher ATP-related measures at rest, paired with a reduced ability to increase energy production when demand rises. The findings, published in Translational Psychiatry, may help explain common symptoms such as fatigue and low motivation, though the work is early and based on a small sample.

Higher midlife vitamin D levels linked to lower brain tau protein

A new study has found that adults with higher vitamin D levels in their 30s and 40s tend to have lower levels of tau protein in their brains about 16 years later. Tau is a key biomarker associated with dementia. The research, published this week, highlights a potential modifiable risk factor for brain health.

Study links brain blood flow changes to Alzheimer's risk

24 فبراير، 2026 من إعداد الذكاء الاصطناعي

New research from the University of Southern California suggests that subtle declines in brain blood flow and oxygen delivery may be early indicators of Alzheimer's disease. The study, published in Alzheimer's and Dementia, used noninvasive scans to connect vascular health with amyloid plaques and hippocampal shrinkage. These findings highlight the role of brain circulation in the disease process beyond traditional markers like amyloid and tau.

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Stroke prompts rejuvenation-like changes in undamaged brain areas

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Regular egg eating linked to lower Alzheimer’s risk

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Lonely older adults have weaker memory but similar decline rates

Blood test forecasts Alzheimer's symptoms years ahead

Scientists at Washington University School of Medicine in St. Louis have developed a blood test that estimates when Alzheimer's symptoms may begin, using levels of the protein p-tau217. The model predicts onset within about three to four years, potentially aiding clinical trials and early interventions. This advance relies on data from 603 older adults in ongoing studies.

UCSF study links iron-associated protein FTL1 to age-related memory decline in mice

5 أبريل، 2026 من إعداد الذكاء الاصطناعي تم التحقق من الحقائق

Researchers at the University of California, San Francisco report that higher levels of the iron-associated protein FTL1 in the hippocampus of older mice are tied to weaker neural connections and worse performance on cognitive tests. In the experiments, reducing FTL1 in older mice was associated with increased neuronal connectivity and improved memory performance, findings published in Nature Aging.

21 مايو 2026 17:55

دراسة تربط بين مستويات فيتامين ب12 الطبيعية المنخفضة وتغيرات في الدماغ

مقالات ذات صلة

Study links major depression in young adults to altered cellular energy patterns in brain and blood

Higher midlife vitamin D levels linked to lower brain tau protein

Study links brain blood flow changes to Alzheimer's risk

Stroke prompts rejuvenation-like changes in undamaged brain areas

Regular egg eating linked to lower Alzheimer’s risk

Lonely older adults have weaker memory but similar decline rates

Blood test forecasts Alzheimer's symptoms years ahead

UCSF study links iron-associated protein FTL1 to age-related memory decline in mice

Women’s verbal memory may delay alzheimer’s diagnosis by years

Study finds alzheimer's risk factors hit women harder

Personalized treatment plans improve early dementia symptoms

Lifelong cognitive enrichment tied to lower Alzheimer’s risk and later symptom onset, study finds

Higher meat intake slows Alzheimer's decline for APOE4 carriers, Karolinska study shows

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