Compostos de especiarias agem em sinergia para potencializar a ação anti-inflamatória centenas de vezes

Pesquisadores da Universidade de Ciência de Tóquio descobriram que a combinação de compostos vegetais comuns de hortelã, eucalipto e pimentas intensifica drasticamente seus efeitos anti-inflamatórios em células imunológicas. Certas combinações ampliaram a resposta centenas de vezes em comparação com o uso individual. As descobertas, publicadas na revista Nutrients, sugerem potencial para novas abordagens dietéticas no combate à inflamação crônica.

Uma equipe liderada pelo professor Gen-ichiro Arimura, da Universidade de Ciência de Tóquio, testou fitoquímicos em macrófagos murinos, células imunológicas fundamentais na inflamação. As células foram expostas a lipopolissacarídeos para simular uma infecção e, em seguida, tratadas com mentol de hortelã, 1,8-cineol de eucalipto, capsaicina de pimentas e β-eudesmol de lúpulo e gengibre, isoladamente ou combinados. A capsaicina apresentou o efeito isolado mais forte, mas surgiram sinergias nas misturas, explicou o professor Arimura: 'Quando a capsaicina e o mentol ou o 1,8-cineol foram usados juntos, seu efeito anti-inflamatório aumentou centenas de vezes em comparação com quando cada composto foi usado sozinho.'

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