世界中で数百万人が変形性関節症に苦しんでいるが、多くの人が最も効果的な治療法である運動を見逃している。専門家は、運動が関節を滋養し、多くの場合で手術や薬よりも痛みを軽減すると指摘している。研究によると、診断された患者の半数未満しか身体活動プログラムへの紹介を受けていない。
変形性関節症は世界で5億9,500万人以上に影響を及ぼしており、平均寿命の延長、座りがちな生活様式、肥満率の上昇により、2050年までに10億人に達する可能性がある。この疾患は、軟骨、液体、骨、靭帯、筋肉、神経を含む関節全体に関与しており、単なる摩耗だけではない。
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In a randomized, sham-controlled trial, adults with mild-to-moderate medial compartment knee osteoarthritis who were retrained to walk with a personalized, small change in foot progression angle reported greater pain improvement after one year than those given sham retraining. The study, conducted at Stanford University and published in The Lancet Rheumatology, also found a smaller MRI-based worsening of a cartilage microstructure measure in the intervention group.
A major review of 217 clinical trials has identified aerobic exercises like walking, cycling and swimming as the most effective for reducing pain and improving function in knee osteoarthritis. The study, published in The BMJ, recommends these activities as the first-line intervention. Other exercises provide benefits but work best alongside aerobics.
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Researchers at the University of Colorado Boulder have demonstrated that a single injected drug-delivery system can reverse osteoarthritis in animals within weeks. The team, led by chemical and biological engineer Stephanie Bryant, reported success in early animal experiments. They aim to advance to human trials after further safety testing.
A Decathlon survey with Consumoteca polled 2,017 people and analyzed over 10 million social media posts, finding that 93% of Brazilians want to exercise but only 44% maintain routines. Lack of motivation tops the barriers at 45%, followed by lack of time (39%) and financial issues (31%). Women report higher issues like harassment.
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A one-year course of the drug abatacept can delay the onset of rheumatoid arthritis by up to four years in high-risk individuals. The benefits persisted long after treatment stopped, according to new research from King's College London.