パーキンソン病の人は、レモンのような心地よい匂いから得られる楽しみが減少するという新たな研究結果がある。この匂いの知覚の違いは、疾患をより早期かつ簡便に診断するのに役立つ可能性がある。研究者らは、影響を受けた人々の脳による香りの処理が異なり、嗅覚喪失のある他の人々から区別できることを発見した。
イスラエルのレホヴォトにあるワイズマン科学研究所のNoam Sobel氏が主導した研究によると、パーキンソン病の人は、健康な人や無関係の嗅覚問題を抱える人とは異なり、心地よい匂いを異なるように知覚する。研究には94人の参加者がおり、主に50代後半から60代後半の年齢：パーキンソン病と診断された33人、医療的な疾患のない33人、疾患と無関係の嗅覚機能障害を持つ28人である。
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A UCLA Health study reports that people with long-term residential exposure to the pesticide chlorpyrifos had more than a 2.5-fold higher likelihood of developing Parkinson’s disease. The research, published in Molecular Neurodegeneration, pairs human exposure estimates with animal and zebrafish experiments that found dopamine-neuron damage and disruptions to the brain’s protein “cleanup” system.
Researchers at Harvard Medical School have uncovered a hidden map of smell receptors in mice noses, revealing neat stripes instead of random distribution. This structure aligns with brain mapping, challenging prior assumptions about olfaction. The findings, published April 28 in Cell, could aid treatments for smell loss.
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Researchers at Emory University have discovered that excessive brain and muscle activity during minor balance disruptions contributes to poorer balance recovery in older adults, including those with Parkinson's disease. The study, published in eNeuro, reveals that trying harder to balance may actually increase fall risk. Opposing muscles stiffening simultaneously further impairs stability.
A new study reveals that after a stroke, the undamaged side of the brain can appear biologically younger as it compensates for lost function. Researchers analyzed MRI scans from over 500 stroke survivors worldwide using AI models. The findings suggest neuroplasticity helps explain persistent motor impairments.
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A study of over 375,000 Finns has linked hospital treatment for severe infections like cystitis and pneumonia to a higher risk of developing dementia within five to six years. Researchers identified 29 conditions associated with at least a 20 percent increased risk, with infections playing a key role. The findings suggest that preventing such infections could help modify dementia risk.