Serotonina pode piorar os sintomas de zumbido, aponta novo estudo

15 de maio de 2026

Reportado por IA

Uma nova pesquisa mostra que a serotonina, um neurotransmissor potencializado por muitos antidepressivos, pode intensificar o zumbido no ouvido. Cientistas identificaram um circuito cerebral específico em camundongos que associa níveis mais elevados de serotonina a comportamentos que mimetizam a condição.

Uma equipe da Oregon Health & Science University e da Universidade de Anhui, na China, publicou as descobertas no periódico Proceedings of the National Academy of Sciences. Os pesquisadores utilizaram optogenética para estimular neurônios produtores de serotonina e observaram um aumento da atividade em regiões auditivas do cérebro, juntamente com respostas semelhantes ao zumbido nos camundongos por meio de um teste de sobressalto modificado. O estudo complementa pesquisas anteriores de 2017 e coincide com relatos de alguns pacientes cujo zumbido piora com o uso de inibidores seletivos da recaptação da serotonina (ISRS).

Study finds infrasound can raise cortisol and irritability even when people can’t hear it

04 de maio de 2026 Reportado por IA Imagem gerada por IA Verificado

A small controlled experiment reported in Frontiers in Behavioral Neuroscience found that exposure to infrasound—ultra-low-frequency vibration below the range of human hearing—was associated with higher salivary cortisol and more negative mood ratings, even though participants could not reliably detect when the infrasound was present.

Study explains psychedelics' effects on brain's visual and memory systems

Researchers have discovered that psychedelic substances suppress visual processing in the brain, leading to hallucinations by drawing on memory fragments. The study, conducted using advanced imaging on mice, shows how slow brain waves shift perception toward internal recall. These findings could inform therapies for depression and anxiety.

24-minute music session reduces anxiety in clinical trial

16 de março de 2026 Reportado por IA

A randomized clinical trial found that 24 minutes of specially designed music paired with auditory beat stimulation significantly lowers anxiety symptoms. Researchers at Toronto Metropolitan University tested various listening durations on 144 adults with moderate anxiety. The 24-minute session provided the strongest benefits.

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UCLA study finds five-day accelerated TMS schedule performed similarly to conventional six-week course for treatment-resistant depression

Researchers at UCLA Health report that delivering transcranial magnetic stimulation (TMS) in an intensive five-day schedule—five sessions per day for five days—was associated with depression symptom improvements comparable to a conventional six-week schedule in a retrospective analysis of 175 patients with treatment-resistant depression. The study also found that some patients who showed little immediate change after the accelerated course improved noticeably in the following weeks.

Single dose of DMT eases depression symptoms in small trial

16 de fevereiro de 2026 Reportado por IA

A small clinical trial has found that a single dose of the psychedelic drug dimethyltryptamine (DMT) led to rapid and sustained reductions in depression symptoms when combined with therapy. Participants experienced improvements lasting up to six months, with mild side effects reported. The study highlights potential benefits of short-acting psychedelics for treatment-resistant depression.

PET brain scans link ketamine’s rapid antidepressant effect to shifts in AMPA receptor availability

A study in Molecular Psychiatry used PET imaging with a new tracer to track changes in AMPA-type glutamate receptors in people with treatment-resistant depression receiving ketamine, reporting that region-specific receptor changes were associated with symptom improvement.

domingo, 10 de maio de 2026, 05:49h

Modified psilocin derivatives show antidepressant-relevant serotonin activity in mice with fewer psychedelic-like effects

sexta-feira, 20 de fevereiro de 2026, 01:55h

Serotonina pode piorar os sintomas de zumbido, aponta novo estudo

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