スペインの大規模臨床試験により、カロリー制限、身体活動、専門家によるサポートを組み合わせた修正版地中海食が、6年間で2型糖尿病の発症リスクを31%低減させることが明らかになった。この研究結果は、過体重または肥満の成人約5,000人を対象とした「PREDIMED-Plus」研究から得られたものである。
研究チームは、代謝症候群を抱えているものの開始時点で糖尿病を患っていない55歳から75歳の参加者4,746人を追跡調査した。一方のグループは、カロリーを抑えた地中海食を採用し、早歩きなどの適度な運動を加え、減量のためのコーチングを受けた。比較対象のグループは、これらの追加要素を含まない標準的な地中海食に従った。
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A new Karolinska Institutet study finds that children with moderate obesity face higher risks of type 2 diabetes, high blood pressure, and lipid disorders in adulthood, even without apparent risk markers. Researchers urge treatment for all such children.
New research published in Nature Medicine reveals that people with prediabetes can normalize blood sugar levels without losing weight. About one in four participants in lifestyle programs achieved this remission, offering protection against diabetes similar to weight loss methods. The key factors involve fat distribution and certain hormones.
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A new study shows that a high-fat ketogenic diet can normalize blood sugar levels in mice with hyperglycemia and enhance their muscles' response to exercise. Led by researcher Sarah Lessard, the research indicates that combining the diet with physical activity leads to better oxygen use and endurance. The findings suggest potential benefits for metabolic health when diet and exercise are paired.
Scientists have developed a hybrid obesity treatment that uses GLP-1 and GIP signals to deliver a metabolic enhancer directly into cells. Early tests in mice showed greater weight loss and better blood sugar control than standard therapies. The approach aims to reduce side effects by limiting the drug's action to targeted areas.
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Researchers have identified why living at high altitudes reduces diabetes risk: red blood cells absorb excess glucose in low-oxygen conditions. This metabolic shift lowers blood sugar levels, as shown in mouse experiments. A new drug mimicking this effect reversed diabetes in mice, suggesting potential treatments.